We offer short and long term toxicity studies for safety assessment of small molecules, biotechnology and agrochemicals. Services offered according to international and national Regulatory Guidelines (OECD, Schedule Y, EU, EPA, ISO, ICH)
- Acute toxicity studies
- Single dose oral and dermal toxicity studies
- Ocular irritation studies
- Guinea pig maximization assays
- Local tolerance studies
- Maximum Tolerated Dose (MTD)
- Long term toxicity studies
- Repeated dose toxicity studies ranging from 28 days to one year duration
- Support services including bioanalysis and pathology
- Reproductive toxicology
- Genetic toxicology
- Ames test-OECD 471
- In vitro micronucleus test- OECD 487
- In vitro chromosomal aberration test- OECD 473
- Mouse lymphoma assay by L5178 OECD -490
- In vivo micronucleus test- OECD 474
- In vitro cell based assays
- Cytotoxicity, cell proliferation and cyto-protective assays
- Apoptosis, cell cycle and DNA damage assays
- Functional cell stress assays
- Skin irritation test OECD-493 using Epiderm/Episkin
- Skin corrosion test OECD-431 using Epiderm/Episkin
- Eye irritation test or serious eye damage OECD-491 using statens serum institut rabbit cornea (SIRC) cells